In earlier studies, it has been reported thatSARS-CoV-2 induced hypoxia causes activation of HIF-1α which is an essential biomarker of acute myeloid leukemia (AML), especially in those patients who haveFlt3-ITD (FMS-like tyrosine kinase-3 receptor internal tandem duplications) mutations. Here, HIF1A is linked to acute myeloid leukemia.