We observed that the final two subgroups responded differently to certain cancer drugs, including AZ628 (RAF inhibitor), A.443654 (AKT inhibitor), A.770041 (Src family Lck inhibitor), AICAR (AMPK activator), AUY922 (HSP-90 inhibitor), ABT.888 and AG.014699 (PARP inhibitors), AMG.706 (VEGFR inhibitor), and AP.24534 (a pan-BCR-ABL inhibitor). This evidence concerns the gene AKT1 and cancer.