CXCL8 and age-related macular degeneration: Liu et al. [40] conducted a similar study in 2017, where, after treating ARPE-19 cells with the same test compounds, they evaluated an increase in the expression of genes by an RT-qPCR reaction, encoding cytokines such as TNF-α, IL-6, and IL-8 associated with inflammatory processes involved in the pathogenesis of AMD.