Among the deregulated genes in the naïve B cells, we found a downregulation of the major histocompatibility complex, Class II, DQ Alpha 1 (HLA-DQA1), and the mitochondrial gene MT-ATP8 (Mitochondrially Encoded ATP Synthase Membrane Subunit 8) in COVID-19-infected subjects compared to the uninfected subject (Figure 3B). Here, MT-ATP8 is linked to COVID-19.