In patients with COVID-19, lymphopenia, thrombocytopenia, and hypoalbuminemia, and increases in D-dimer, C-Reactive Protein (CRP), creatinine, aminotransferases, cardiac troponins, total bilirubin, erythrocyte sedimentation rate, prothrombin time, and procalcitonin values come to the fore. The gene discussed is CRP; the disease is lymphopenia.