We found levels of the endolysosomal marker LAMP1 are increased in CA1 and CA3 regions of AD hippocampi, and are enriched around senile plaques, consistent with previous analysis in the AD frontal cortex (Barrachina et al., 2006; Bordi et al., 2016; Piras et al., 2016). The gene discussed is LAMP1; the disease is Alzheimer disease.