Studies have found that Hsp90 levels and related ATPase activities are elevated in IPF lung and mouse pulmonary fibrosis models, and inhibition of Hsp90 and related ATPase activities can attenuate fibroblast activation, migration, proliferation, invasiveness, attenuate ECM production, and alleviate pulmonary fibrosis, and its inhibitors have been used in the clinical treatment of pulmonary fibrosis [91]. Here, DNAH8 is linked to idiopathic pulmonary fibrosis.