The production of ROS, which is a major anti‐myeloma activity of GTN024,18 is not the only antiproliferative mechanism of GTN057; we observed herein that GTN057 inhibited HGF receptor/c‐Met in addition to the downstream signaling mediated by ERK1/2, STAT3, and AKT1. The gene discussed is STAT3; the disease is plasma cell myeloma.