This is especially true in children, and insulin ranks as the third most common cause of medication errors in hospitalized children within the United States.1 While the American Diabetes Association recommends that children with diabetes receive care from pediatric endocrinologists,2 the relative shortage of pediatric endocrinologists3 has led to an increasing need for generalists to be prepared to care for children with insulin-dependent diabetes. The gene discussed is INS; the disease is diabetes mellitus.