TNF and infection: Furthermore, it was also reported that miR-2187, miR-30c-3-3p, or miR-146a may possibly depress the expression of inflammatory factors (e.g., TNF-α, IL-8, or IL-1β) in an indirect way in the liver, kidney, and spleen cells of miiuy croaker or in the spleen of E. coioides after LPS stimulation or infection by RGNNV or SCRV (16, 44, 85).