AT-MSCs can effectively inhibit the proliferation and division of HCC cells and induce HCC cell death by downregulating the Akt signaling pathway [27].UC-MSCs inhibit the proliferation of prostate cancer PC-3 cells by activating JNK and downregulating PI3K/AKT signals under coculture conditions [28]. The gene discussed is MAPK8; the disease is hepatocellular carcinoma.