Chemokines produced by tumor cells, immune cells, and tumor stromal cells, including CC­chemokine ligand 2 (CCL2), CCL5, CXC­chemokine ligand 12 (CXCL12, also known as SDF1) and CXCL1, are involved in this process [11–14]. Here, CXCL1 is linked to neoplasm.