Core immuno-inflammatory pathways such as Toll, JAK/STAT, and immunodeficiency (Imd) equivalent to TLR-4, JAK/STAT and TNF pathways in mammals (Hoffmann and Reichhart, 2002; Hoffman, 2003; Myllymäki et al., 2014) are also present in Drosophila. These innate immune-inflammatory pathways, whether in humans or Drosophila, respond to infection and aging/injury by promoting the expression of inflammatory mediators such as cytokines and antimicrobial peptides (AMPs in fly and humans) (Myllymäki et al., 2014). This evidence concerns the gene SOAT1 and immune system disorder.