It is worth noting that several terms related to extracellular matrix (ECM) had also been enriched, involving “Mucin type O−Glycan biosynthesis,” “ECM−receptor interaction” (Supplementary Figure S2) and “Proteoglycans in cancer.” Of note, using clustering analysis, we found that ECM and stemness were clustered together, implying that the MSCs stemness might be closely pertinent with the deposition or balances of ECM (Figure 1E). This evidence concerns the gene MUC5AC and cancer.