MTOR and neurodegenerative disease: Growing evidence indicates that the mTOR signaling pathway is an essential regulator of neuronal development, survival, differentiation, and synaptic plasticity (Jaworski and Sheng, 2006; Meng et al., 2018), and the mTOR signaling pathway is also associated with the pathogenesis of a broad range of neurological diseases, including neurodevelopmental disorders and neurodegenerative diseases (Costa-Mattioli and Monteggia, 2013; Perluigi et al., 2015).