ST8SIA1 and neuroblastoma: The transfection of GD3S cDNA into a neuroblastoma cell line (SH-SY5Y), which highly expressed GM2 and GD1a but does not express GD3 and GD2, resulted in the upregulation of GD3 and GD2 expression, a more dispersed cell growth pattern, and a lower growth rate (Ruan et al., 1999).