TGM2 and type 2 diabetes mellitus: Next, to characterize the potential effect of each allele in rs2076380 SNP on the expression of both, LncTGM2 and TGM2, we constructed two LncTGM2 overexpression plasmids, one harboring the T2D risk allele (ovLncTGM2-A), and the other harboring the T2D protective allele (ovLncTGM2-G).