Except for the #8 clone, galectin-3-knockdown clones significantly produced lower levels of the viral NS1 protein, which is preferentially synthesized at early times of infection [34], at 7 h p.i. (Fig. 3c) and generated lower viral titers at 24 and 48 h (Fig. 3d) compared to vector control cells. The gene discussed is PTPN11; the disease is infection.