GPT and obesity due to melanocortin 4 receptor deficiency: Overall, 73 patients (5.4%) presented altered levels of AST or ALT, which was found to be higher in patients with overweight/obesity compared to patients with normal weight, 39 (7.1%) vs 34 (4.2%), p = 0.02, respectively, and in women compared to men 50 (68.5%) vs 23 (31.5%), p = 0.047, respectively.