NSE in cord blood and cerebral blood flow (CBF) in early-onset neonatal sepsis (EONS) were examined to predict SAE occurrence and showed that increased cord blood NSE and CBF in early hours of birth could be used in neonates with EONS with a predictive accuracy of SAE (Shimy et al. 2018). The gene discussed is ENO2; the disease is Neonatal sepsis.