CRP and infection: Infections were defined as a positive bacteriological sample with clinical or biological signs of infection, or all criteria for a severe infection [hemodynamic instability (increased vasoplegia or need for increased VA-ECMO support), fever (> 38 C under VA-ECMO), low/high white blood cell (< 4 G/L or > 12 G/L), systemic inflammation (CRP > 20 mg/L)] without any positive bacterial growth [5, 9].