IL17A and Anxiety: In the open-field test, the total distance travelled showed no significant differences among the three groups (Fig. 3E), indicating that locomotion activity was not influenced by Aβ42 and IL-17Ab treatment, but the time spent in the center was reduced in the Aβ42 group compared with the control group and ameliorated by the administration of IL-17Ab (Fig. 3F), indicating that inhibition of IL-17 might reduce anxiety.