GSTM1 and anemia (phenotype): Recently, a clinical algorithm for the diagnosis and treatment of anemia in RDEB patients was proposed: (i) start enteral iron if Hb ≤ 100 g/L after performing an enteral iron absorption test, as this may help to determine whether parental iron is indicated instead, (ii) consider IV iron if Hb is between 80 and 100 g/L and, (iii) consider blood transfusion if Hb is < 80 g/L [14].