The GRP-increasing G-allele of the lead cis-pQTL (rs1517035; MAF=0.18) was associated with a reduced risk for T2D in the largest T2D study (25) (OR [95% CI] = 0.96 [0.95-0.98], p-value=7.8x10-10). Here, GRP is linked to type 2 diabetes mellitus.