LDHA and neoplasm: Next, we treated tumor-bearing wild-type mice or LysM-Cre LdhAfl/fl mice (referred to as Ldha conditional knockout mice, LdhAcKO) with FGK45 monoclonal antibodies and found that TAMs from LdhAcKO mice displayed reduced expression of LdhA compared to TAMs from wild-type mice (Extended Data Fig. 5e,f).