To identify tumour tissues that show the most significant differences in PLEKHA7 expression, we performed immunohistochemistry (IHC) staining to detect the PLEKHA7 expression levels in tissue samples of common types of cancers (lung adenocarcinoma (LUAD), colon adenocarcinoma (COAD), liver hepatocellular carcinoma (LIHC), kidney renal clear cell carcinoma (KIRC), prostate adenocarcinoma (PRAD), stomach adenocarcinoma (STAD), and breast cancer (BC)) and compared these levels to those in paired normal tissues. This evidence concerns the gene PLEKHA7 and lung adenocarcinoma.