The results of this and previous studies have shown the loss of PLEKHA7 expression in tumour tissues [26, 31] and elucidated the roles that PLEKHA7 plays in regulating tumourigenesis and metastatic miRNA levels [24, 30, 32], implicating PLEKHA7 in critical regulatory tumour invasion and metastasis mechanisms. This evidence concerns the gene PLEKHA7 and neoplasm.