CD68 and granular cell tumor: As shown in Fig. 6G, H and Supplementary Fig. S5E, we found a greater number of invasive CD68 + macrophages in the tumors of the RRX-001-treated group than in the control group as early as 1 week after RRX-001 treatment (2 weeks after transplantation), showing that suppressing Cd47 in GCT cells dramatically increases macrophage invasion.