We applied Downstreamer56 to SCZ57, PD58, MS29, AD59 and amyotrophic lateral sclerosis (ALS) GWAS summary statistics60, using these networks to prioritize genes that are co-regulated with genes in their GWAS loci (Supplementary Note, Supplementary Fig. 34 and Supplementary Tables 25–30). The gene discussed is DAP3; the disease is amyotrophic lateral sclerosis.