Snail knockdown inhibited the growth of HM-1 mouse ovarian cancer cell in immunocompetent mice, accompanied by an increase in CD8+ TILs and a decrease in MDSCs, by reducing the levels of the (C-X-C Motif) chemokine receptor 2 (CXCR2) ligands, chemokine (C-X-C motif) ligand 1/2 (CXCL1/2) [174]. This evidence concerns the gene CXCR2 and ovarian cancer.