Due to the tumor-promoted mechanisms of HOXC11 remains unclear, we used GSEA to enrich some HOXC11 expression-related genes, including CCL5, HBA2, and SPHK1 (Fig. 5a), and then detected their mRNA expressive levels in HOXC11 overexpressed cells (Fig. 5b). The gene discussed is HBA2; the disease is neoplasm.