Laboratory tests revealed high INR (1.37), increased serum direct and indirect bilirubin levels (8.49 and 7.22 mg/dL), elevated liver enzymes (aspartate aminotransferase [AST] 492 U/L and alanine aminotransferase [ALT] 189 U/L), thrombocytopenia (platelets 52,000/mm3), leukocytosis (24,300 cells/mm3) with an increase in neutrophil proportion (6% rods and 81% segmented cells), and acute renal failure (creatinine 4.8 mg/dL, urea 131 mg/dL). The gene discussed is GPT; the disease is acute kidney injury.