YY1 is involved in cell growth, proliferation, and transformation, and has been shown to be overexpressed in many cancers, making YY1 a promising novel target for cancer treatment.[51] It was found that the YY1-related signaling axis contributes to NSCLC cell proliferation, migration and invasion; therefore, YY1 is considered an oncogene in lung cancer,[52] which is consistent with our findings. This evidence concerns the gene YY1 and cancer.