ETV6 and adrenal cortex carcinoma: Mammary analogue secretory carcinomas can also occur in the lungs and are very similar to ACC in morphology, making it difficult to differentiate between the 2 types.[27,28] However, mammary analogue secretory carcinoma of the lung was also observed to harbor ETV6-NTRK3 rearrangements and was positive for mammaglobin and S-100, which cannot be detected in cases of ACC.[27]