FLG and candidiasis: IL17 plays a vital role in the mucoepithelial defenses against Candida infections.[4] Moreover, studies on mouse model suggest that IL-17A has a significant role in maitaining the skin microbiome homeostasis and in the expression of filaggrin.[4,10] Consequently, several researchers speculated that preventing Th1 and Th17 cytokines could induce an imbalance in Th2 prominent immune responses.