GO analysis results showed that the biological process of TBFS in the treatment of COPD mainly involved positive regulation of calcidiol 1-monooxygenase activity, heat generation, adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, and hormone response. The gene discussed is CYP27B1; the disease is chronic obstructive pulmonary disease.