To estimate the mechanism of USP21 promoting the migration, invasion, and stemness profiles of nasopharyngeal carcinoma cells by the FOXM1 pathway, western blot assay was used to check the expression of FOXM1 in nasopharyngeal carcinoma cells after sh-USP21#1 and sh-USP21#2 transfection. Here, USP21 is linked to nasopharyngeal carcinoma.