Among them, 17 genes were up-regulated including SLC22A4, MBOAT2, TSPO, NFE2, GCLM, FLVCR2, ATP6V1C1, CYP1B1, LCN2, AHSP, CLIC2, LTF, ELL2, CISD2, CA1, RHAG, and GYPA, while 4 genes were down-regulated including ALOX15, BCL2, FTO, and CYP4V2 in sepsis compared with the non-sepsis or healthy controls. The gene discussed is NFE2; the disease is Sepsis.