ALK and non-small cell lung carcinoma: Recently, a retrospective study of 21 patients with BMs from EGFR/ALK-negative NSCLC also found the concurrent WBRT and ICIs prolonged CNS-PFS (HR: 0.29, 95% CI: 0.11–0.80; P = 0.016) and OS (HR 0.33, 95% CI: 0.08–1.12; P = 0.107) than WBRT alone [72].