APOE and Schnyder corneal dystrophy: A significant interaction of APOE genotype with SCD on brain activation was found in the following ROIs: anterior cingulate [F(1,209) = 4.527, p = 0.003], inferior frontal [F(1,209) = 4.231, p = 0.041], middle frontal [F(1,209) = 3,959, p = 0.048], and superior frontal gyri [F(1,209) = 4.414, p = 0.037].