UNC13A and frontotemporal dementia: Only a limited number of studies have investigated the relationship of UNC13A with behavioral and cognitive features of ALS patients, highlighting an association of the minor C allele with imaging, neuropsychological and pathological markers of FTD in ALS, as well as with higher rates of reported disinhibition and behavioral impairment (Placek et al., 2019; Tan et al., 2020).