When excluding children diagnosed with either β‐thalassemia or a β‐globin variant, the median HbA2 level did not vary between the α‐thalassemia children and the non‐α‐thalassemia children, except in the two children with HbH disease who had considerably lower HbA2 levels than the non‐α‐thalassemia children (1.2 [1.0–1.3] versus 2.4 [2.1–2.7]). This evidence concerns the gene HBA2 and alpha thalassemia spectrum.