cResponders’ factors; Dyslipidemia-redox balance inflammation related factor: TOS, TAS, PAB, PCSK9 and CRP; Coronary risk intervention-related factor: Total CK activity, ALT, AST and octacosanol supplement; Lipid risk-protein related redox factor: AOPP, SHG and ApoB100; Metabolic-related antioxidant factor: ApoA1, Glucose and PON1. This evidence concerns the gene PON1 and metabolic syndrome.