TAI-thyroid autoimmunity referring to the presence of serum thyroid autoantibodies (thyroid peroxidase antibodies and/or thyroglobulin antibodies); TSH-thyrotropin; fT4-free thyroxine; fT3-free triiodothyronine; TPOAbs-thyroperoxidase antibodies; TgAbs-thyroglobulin antibodies; FF-follicular fluid; P4-progesterone. The gene discussed is TPO; the disease is autoimmune thyroid disease.