In addition to the intracellular tumorigenic role of mortalin in above malignant tumors, exosomes derived from tumor cells of breast, ovarian, prostate, hepatic, gastric, colon, but not pancreatic carcinoma have high levels of mortalin expression compared to normal tissues (Huang et al., 2019). The gene discussed is HSPA9; the disease is exocrine pancreatic carcinoma.