However, ABC transporter’s role is not limited to chemotherapeutics efflux, they also play a role in a variety of cancer hallmarks such as enhanced proliferation (Bhattacharya et al., 2007; Katoh, et al., 2008), resistance to cell death (Smyth et al., 1998; Tainton et al., 2004), migration and invasion (Miletti-González et al., 2005; Colone et al., 2008). This evidence concerns the gene ABCG2 and cancer.