Meanwhile, the supplementation of probiotic Lactobacillus rhamnosus GG (LGG) might improve intestinal integrity by inhibiting miR122a, which resulted in occludin restoration, and increasing mRNA expression of tight junction (TJ) proteins in mice with alcohol-induced liver injury (Zhao et al., 2015; Chen et al., 2016). The gene discussed is OCLN; the disease is injury.