CADM1 and neoplasm: Another adhesion molecule, the cell adhesion molecule 1 (CADM1), with multiple functions, has been identified as a tumor suppressor gene (Sawada et al., 2020) and was found to exhibit significant communication through CADM1-CADM1 homophilic binding only in SGCs-NP (Figure 5F), which may indicate to some extent the specificity of NP subtype.