This study used semi-quantitative analysis to calculate the standard intake lean body mass (SULpeak) and TLG values ​​of the hottest lesions in all patients. Among responders and non-responders, EGFR18F -FDG SULpeak is better than18F-FLT SULpeak in predicting OS and PFS in NSCLC patients treated with EGFR-TKI for 3 weeks. This evidence concerns the gene EGFR and non-small cell lung carcinoma.