DSP and Microcephaly - facio-cardio-skeletal syndrome, Hadziselimovic type: The Dsp null genotype, which was induced specifically in the post-natal myocytes, represents the recessive and compound mutations in the human DSP gene, which are established causes of ACM and the cardiocutaneous syndromes characterized by DCM, woolly hair, and keratoderma[14,43,44].