lncRNA Linc00662 has been shown to promote tumorigenesis in PC (Yao et al., 2020), CHASERR, an evolutionary conserved lncRNA, regulates the levels of chromatin remodeling protein CHD2 (Antonov and Medvedeva, 2020), whereas the role of the third lncRNA identified in this study is unknown. Here, CHASERR is linked to pachyonychia congenita.