LCP1 was correlated with lymph node metastasis and proposed as independent PC prognostic factor (Chen et al., 2017), while GLO1 might serve as a high-grade prostatic intraepithelial neoplasia marker (Rounds et al., 2021) and is strongly linked to early biochemical recurrence (Burdelski et al., 2017). This evidence concerns the gene LCP1 and pachyonychia congenita.