Mutations found more commonly in ABC or GCB subtypes respectively further add defining features and explanation to their course, such as N1 subtype appearing in ABC 95% of the time, or the observed co-occurrence of EZH2 mutations with BCL2 translocations in GCB type lymphomas (Figure 1B) (Miao et al., 2019). This evidence concerns the gene BCL2 and lymphoma.